Regadenoson: A New Myocardial Stress Agent

Regadenoson: a new myocardial stress agent.

Vasodilator stress myocardial perfusion imaging (MPI) accounts for up to 50% of all stress MPI studies performed in the U.S. In 2008, the Food and Drug Administration approved regadenoson for stress testing in conjunction with MPI. Regadenoson, unlike adenosine, is a selective A(2A) agonist that is given as an intravenous bolus at a fixed dose, with less undesirable side effects including atrio...

[Regadenoson as a new stress agent in myocardial perfusion imaging. Initial experience in The Netherlands].

OBJECTIVE Regadenoson is a recently approved selective adenosine-2A receptor agonist to induce pharmacological stress in myocardial perfusion imaging (MPI) procedures using a single bolus injection. MATERIAL AND METHODS We included 123 patients referred for MPI because of suspected coronary arterial disease (CAD). Of these, 66 patients underwent a regadenoson stress test and 57 patients under...

Regadenoson Cardiac Stress Myocardial Perfusion Scintigraphy

Initial results of a new very rapid rest/regadenoson stress myocardial perfusion protocol in patients with atrial fibrillation

Background Cardiovascular magnetic resonance (CMR) myocardial perfusion is a well established method for detection of significant obstructive coronary artery disease (CAD). In patients with arrhythmias, standard methods using ECGgating can result in poor image quality. Additionally, with typical stress/rest protocols, a true rest state may not be achieved after administration of regadenoson. Ho...

Detection of obstructive coronary artery disease using regadenoson stress and 82Rb PET/CT myocardial perfusion imaging.

UNLABELLED Our objective was to study the diagnostic performance of regadenoson (82)Rb myocardial perfusion PET imaging to detect obstructive coronary artery disease (CAD). METHODS We studied 134 patients (mean age, 63 ± 12 y; mean body mass index, 31 ± 9 kg/m(2)) without known CAD (96 with coronary angiography and 38 with low pretest likelihood of CAD). Stress left ventricular ejection fract...